Pharmacological Perspectives of Toxic Chemicals and Their Antidotes

Front Cover
S.J.S. Flora, James A. Romano, Steven I. Baskin, K. Sekhar
Springer Science & Business Media, Sep 10, 2004 - Medical - 484 pages

The book provides up-to-date pharmacological and toxicological information on chemical warfare agents, industrial chemicals, environmental toxins, metalloid and array of miscellaneous agents including their mechanism of toxicity. Chemical warfare is becoming a major force due to the fact that these agents can provide a substantial psychological edge to the military establishments. It covers topics of current interest like pharmacology of nitric oxide, oxidative stress, modulation of brain cytochrome p450s by environmental chemicals, modalities of nociception and the underlying molecular mechanisms including areas of pharmacology and toxicological interest never discussed in detail like capsaicin, cyanide, arsenic toxicity and cyanobacterial toxin etc. A number of antidotes, which are being used, or currently being investigated, for the treatments of the above toxicants are also discussed in this book. This volume with contributions from leading experts from the USA, Germany and India is a valuable source of information on many areas of pharmacology and toxicological significance for military personnel, scientific professionals in pharmacology, toxicology, biochemistry and environmental sciences.

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Contents

IV
3
V
13
VI
25
VII
41
VIII
51
IX
67
X
87
XIV
97
XXIV
263
XXV
271
XXVII
303
XXVIII
331
XXX
357
XXXI
359
XXXII
383
XXXVI
395

XV
105
XVII
147
XVIII
169
XIX
179
XX
197
XXI
213
XXII
215
XXIII
241
XXXVII
411
XXXVIII
431
XXXIX
445
XL
467
XLI
479
XLII
483
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