Contaminants in the Environment: A Multidisciplinary Assessment of Risks to Man and Other OrganismsThis book provides a broad, interdisciplinary assessment of the hazards presented by direct and indirect environmental contaminants to humans. It explores disparate aspects of risk assessment ranging from molecular mechanisms to the practical and administrative issues of environmental management. The book's first three sections focus on principles relevant to living organisms in general, the fourth addresses the question of risks to human health, while the final section considers issues relevant to both "human" and "natural" environments. |
Contents
Value and limitations of evaluative models in field situations | 3 |
Fate of persistent organochlorines in the marine environment | 19 |
Biological monitoring | 29 |
A summing up | 37 |
Comparative metabolism and selective toxicity | 65 |
Comparative aspects of the metabolism and toxicity of xenobiotics | 75 |
The role of cytochrome P450 in drug metabolism and toxicity | 81 |
Estimation of induction of enzymes that metabolize xenobiotics in vitro | 93 |
Biochemical responses as indicators | 105 |
Reactions of molluscan lysosomes as biomarkers of pollutantinduced | 111 |
Converging epidemiologic findings on radon in mines and homes | 221 |
The role of microorganisms in the environment decontamination | 235 |
Contributions of the World Health Organization to pesticide safety | 257 |
World policy in the new environmental age | 263 |
277 | |
Common terms and phrases
acid activity animals applicators aquatic aromatic arsenic assessment bioaccumulation bioassay Biochem Biol biological monitoring biomarkers biomonitoring cancer risks carcinogenic cells cellular Chem chemicals compounds concentrations contaminants copper cytochrome P-450 degradation dioxins dose drinking water drug ecological ecotoxicity ecotoxicological ecotoxicology effects Environ environmental enzymes epidemiological esterases estimated evaluation exposed exposure factors fish gill hazard Health human increased indices indoor radon induced ingestion inhalation inhibition inorganic arsenic insecticides interaction isozymes JMPR kidney laboratory levels lichens liver lung cancer lymphoma lysosomal measured membrane metabolism metabolites metal microsomal monooxygenase mortality mussels Mytilus edulis organisms organochlorine oxidative pathways PCBs pesticides Pharmacol Phenobarbital phenoxy herbicides pollution population potential protein pulmonary radon radon progeny rats reaction residues response samples sediment serum soft-tissue sarcoma species substrate Table TCDD tissue toxicity toxicity testing Toxicol toxicology vapor vitro xenobiotics µg/L