Infection and AutoimmunityYehuda Shoenfeld, Nancy Agmon-Levin, Noel R. Rose Infection and Autoimmunity encompasses the different mechanisms involved in the infection-autoimmunity association/induction. Special attention is given to heat shock proteins (HSPs) and to transgenic mouse models to better understand infection-induced autoimmunity. Organized into six parts, this book first discusses the mechanisms of autoimmune induction by infection. Some chapters follow discussing the vaccination and vaccines, including the controversial issue of vaccine-autoimmunity relationship. Other chapters elucidate the relationship of bacteria and parasites to autoimmunity. Lastly, the aspects of infections and diseases are described. This reference material will help readers gain a deeper insight into the important etiological aspects of autoimmunity.
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Page 25
... role of conventional environment in facilitating the induction of an autoimmune disease has been observed in various models of autoimmunity (e.g., EAE, thyroiditis, hemolytic anemia, Pristane-induced arthritis (PIA) etc.) [53–58]. In ...
... role of conventional environment in facilitating the induction of an autoimmune disease has been observed in various models of autoimmunity (e.g., EAE, thyroiditis, hemolytic anemia, Pristane-induced arthritis (PIA) etc.) [53–58]. In ...
Page 32
... role of B cells as APC in the diversification of the T cell and antibody response [142]. According to this model, the initial T cell priming to self epitopes is done by APC like dendritic cells, and these activated T cells then provide ...
... role of B cells as APC in the diversification of the T cell and antibody response [142]. According to this model, the initial T cell priming to self epitopes is done by APC like dendritic cells, and these activated T cells then provide ...
Page 33
... role in induction of Th1-mediated diseases. However, the results of studies in various experimental models of autoimmunity (e.g., AA [147], EAE [148–152], collageninduced arthritis (CIA) [153, 154], diabetes in the NOD mouse [155, 156] ...
... role in induction of Th1-mediated diseases. However, the results of studies in various experimental models of autoimmunity (e.g., AA [147], EAE [148–152], collageninduced arthritis (CIA) [153, 154], diabetes in the NOD mouse [155, 156] ...
Page 35
... role of components of innate immunity in autoimmunity, it has recently been shown that the complement and complement receptors [180] play a critical role in mediating effector arthritogenic response in KXBN transgenic mice [181], and in ...
... role of components of innate immunity in autoimmunity, it has recently been shown that the complement and complement receptors [180] play a critical role in mediating effector arthritogenic response in KXBN transgenic mice [181], and in ...
Page 42
... role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. J Immunol 1996;157(8):3223–7. Krakowski M, Owens T. Interferon-gamma confers resistance to experimental allergic ...
... role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. J Immunol 1996;157(8):3223–7. Krakowski M, Owens T. Interferon-gamma confers resistance to experimental allergic ...
Contents
1 | |
5 | |
85 | |
121 | |
Bacteria and Autoimmunity | 319 |
Parasites and Autoimmunity | 437 |
Infection and Diseases | 471 |
Subject Index | 741 |
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Infection and Autoimmunity Yehuda Shoenfeld,Nancy Agmon-Levin,Noel Richard Rose,Y. Shoenfeld Limited preview - 2004 |
Common terms and phrases
activation acute agents animals anti antibodies antigens arthritis Arthritis Rheum associated autoantibodies autoimmune disease bacterial binding blood cause cells chronic Clin clinical clones common complex controls cross-reactive cytokines damage demonstrated detected determined diabetes effects epitope et al evidence experimental expression factor frequency function gene genetic heart hepatitis host human immune response Immunol important increased individuals induced infection inflammatory initial involved lead levels liver lymphocytes major mechanisms mice molecular mimicry molecules multiple sclerosis myocarditis myosin Nature normal observed occur pathogenesis patients peptide peripheral persistent possible present production protein pylori reactive recent receptor recognized reported rheumatic fever risk role sequence serum severe showed shown similar specific spreading stimulation suggested syndrome synovial fluid T-cell therapy thyroid tion tissue treatment trigger type 1 diabetes vaccine vasculitis viral viral infection virus viruses
Popular passages
Page 147 - Navarro for their help in preparing the manuscript. This work was supported in part by CONACyT, Mexico and Fundacion RJ Zevada.
Page 54 - T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 1990; 346: 183-1 87.
Page 287 - Family study of the major histocompatibility complex in patients with systemic lupus erythematosus: importance of null alleles of C4A and C4B in determining disease susceptibility.
Page 147 - Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev 2001;182:18-32.
Page 283 - Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome Iq in African-American pedigrees. Proc Natl Acad Sci USA 1998:95(25): 14869-14874.
Page 168 - Wucherpfennig KW, Strominger JL 1995. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein.
Page 72 - Ledbetter JA, Evans RL, Lipinski M, Cunningham-Rundles C, Good RA, Herzenberg LA: Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and cytotoxic/suppressor subpopulations in mouse and man.
Page 607 - A randomized trial comparing intravenous immune globulin and plasma exchange in Guillain-Barre syndrome.
Page 529 - Jerne NK, Towards a network theory of the immune system.
Page 245 - BURGESS, JA : High frequency of diabetes mellitus in young adults with congenital rubella.