Infection and AutoimmunityYehuda Shoenfeld, Nancy Agmon-Levin, Noel R. Rose Infection and Autoimmunity encompasses the different mechanisms involved in the infection-autoimmunity association/induction. Special attention is given to heat shock proteins (HSPs) and to transgenic mouse models to better understand infection-induced autoimmunity. Organized into six parts, this book first discusses the mechanisms of autoimmune induction by infection. Some chapters follow discussing the vaccination and vaccines, including the controversial issue of vaccine-autoimmunity relationship. Other chapters elucidate the relationship of bacteria and parasites to autoimmunity. Lastly, the aspects of infections and diseases are described. This reference material will help readers gain a deeper insight into the important etiological aspects of autoimmunity.
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Page 14
... pathogenic. EAE has been induced in different strains of mice and in Lewis rats with mimicry peptides of MBP and ... pathogens that carry such T cell epitopes. To address this question, Olson et al. [29] generated recombinant Theiler's ...
... pathogenic. EAE has been induced in different strains of mice and in Lewis rats with mimicry peptides of MBP and ... pathogens that carry such T cell epitopes. To address this question, Olson et al. [29] generated recombinant Theiler's ...
Page 22
... pathogenesis of active vs. passive disease resulting from activation of T cells against the same autoantigen ... pathogenic epitope may not correlate with the presence or absence of clinical signs of the disease. Furthermore ...
... pathogenesis of active vs. passive disease resulting from activation of T cells against the same autoantigen ... pathogenic epitope may not correlate with the presence or absence of clinical signs of the disease. Furthermore ...
Page 24
... pathogenic (180–188/ 177–191 determinant) and regulatory (BCTD) epitopes could explain, in part, the AA-resistance of WKY rats. The results of our recent study demonstrate that the C-terminal epitopes of self hsp65 are also disease ...
... pathogenic (180–188/ 177–191 determinant) and regulatory (BCTD) epitopes could explain, in part, the AA-resistance of WKY rats. The results of our recent study demonstrate that the C-terminal epitopes of self hsp65 are also disease ...
Page 25
... pathogenesis of this disease. However, recent studies have shown that in addition to possessing disease-regulating T ... pathogenic T cell repertoire in this disease. 2.4. Systemic Lupus Erythematosus Systemic lupus erythematosus (SLE) ...
... pathogenesis of this disease. However, recent studies have shown that in addition to possessing disease-regulating T ... pathogenic T cell repertoire in this disease. 2.4. Systemic Lupus Erythematosus Systemic lupus erythematosus (SLE) ...
Page 29
... pathogenesis of Lyme arthritis [114]. In one study, diversification of the antibody response to different antigens of ... pathogenic effector mediators (Table 2), various mechanisms have been proposed to explain the phenomenon of epitope ...
... pathogenesis of Lyme arthritis [114]. In one study, diversification of the antibody response to different antigens of ... pathogenic effector mediators (Table 2), various mechanisms have been proposed to explain the phenomenon of epitope ...
Contents
1 | |
5 | |
85 | |
121 | |
Bacteria and Autoimmunity | 319 |
Parasites and Autoimmunity | 437 |
Infection and Diseases | 471 |
Subject Index | 741 |
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Infection and Autoimmunity Yehuda Shoenfeld,Nancy Agmon-Levin,Noel Richard Rose,Y. Shoenfeld Limited preview - 2004 |
Common terms and phrases
activation acute agents animals anti antibodies antigens arthritis Arthritis Rheum associated autoantibodies autoimmune disease bacterial binding blood cause cells chronic Clin clinical clones common complex controls cross-reactive cytokines damage demonstrated detected determined diabetes effects epitope et al evidence experimental expression factor frequency function gene genetic heart hepatitis host human immune response Immunol important increased individuals induced infection inflammatory initial involved lead levels liver lymphocytes major mechanisms mice molecular mimicry molecules multiple sclerosis myocarditis myosin Nature normal observed occur pathogenesis patients peptide peripheral persistent possible present production protein pylori reactive recent receptor recognized reported rheumatic fever risk role sequence serum severe showed shown similar specific spreading stimulation suggested syndrome synovial fluid T-cell therapy thyroid tion tissue treatment trigger type 1 diabetes vaccine vasculitis viral viral infection virus viruses
Popular passages
Page 147 - Navarro for their help in preparing the manuscript. This work was supported in part by CONACyT, Mexico and Fundacion RJ Zevada.
Page 54 - T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 1990; 346: 183-1 87.
Page 287 - Family study of the major histocompatibility complex in patients with systemic lupus erythematosus: importance of null alleles of C4A and C4B in determining disease susceptibility.
Page 147 - Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev 2001;182:18-32.
Page 283 - Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome Iq in African-American pedigrees. Proc Natl Acad Sci USA 1998:95(25): 14869-14874.
Page 168 - Wucherpfennig KW, Strominger JL 1995. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein.
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Page 607 - A randomized trial comparing intravenous immune globulin and plasma exchange in Guillain-Barre syndrome.
Page 529 - Jerne NK, Towards a network theory of the immune system.
Page 245 - BURGESS, JA : High frequency of diabetes mellitus in young adults with congenital rubella.