Infection and AutoimmunityYehuda Shoenfeld, Nancy Agmon-Levin, Noel R. Rose Infection and Autoimmunity encompasses the different mechanisms involved in the infection-autoimmunity association/induction. Special attention is given to heat shock proteins (HSPs) and to transgenic mouse models to better understand infection-induced autoimmunity. Organized into six parts, this book first discusses the mechanisms of autoimmune induction by infection. Some chapters follow discussing the vaccination and vaccines, including the controversial issue of vaccine-autoimmunity relationship. Other chapters elucidate the relationship of bacteria and parasites to autoimmunity. Lastly, the aspects of infections and diseases are described. This reference material will help readers gain a deeper insight into the important etiological aspects of autoimmunity.
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From inside the book
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Page 29
... inflammatory conditions. Native self and foreign antigens possess potential T cell epitopes that are Table 3. Proposed mechanisms underlying the phenomenon of epitope spreading 1. Upregulation of the display of cryptic/sub-dominant ...
... inflammatory conditions. Native self and foreign antigens possess potential T cell epitopes that are Table 3. Proposed mechanisms underlying the phenomenon of epitope spreading 1. Upregulation of the display of cryptic/sub-dominant ...
Page 30
... inflammatory milieu that is conducive to upregulation of antigen processing and presentation. In addition, the inflammatory events, either of autoimmune origin or induced by a microbial infection, cause tissue damage leading to the ...
... inflammatory milieu that is conducive to upregulation of antigen processing and presentation. In addition, the inflammatory events, either of autoimmune origin or induced by a microbial infection, cause tissue damage leading to the ...
Page 57
... inflammation are common and correspondingly in a broad spectrum of heterogeneous infectious diseases. In infectious diseases inflammation reflects the ability of the adaptive immune system to actively compete with “nonself”. Inflammatory ...
... inflammation are common and correspondingly in a broad spectrum of heterogeneous infectious diseases. In infectious diseases inflammation reflects the ability of the adaptive immune system to actively compete with “nonself”. Inflammatory ...
Page 59
... inflammatory potency in a reconvalescent host either unmasks subclinical disease or worsens intensity of an already apparent inflammation. By certain clinical characteristics progress of classical overt disease can be distinguished from ...
... inflammatory potency in a reconvalescent host either unmasks subclinical disease or worsens intensity of an already apparent inflammation. By certain clinical characteristics progress of classical overt disease can be distinguished from ...
Page 61
... inflammatory syndromes (IRIS) present as unexpected event or paradoxical deterioration of inflammation. IRIS is correlated to a variety of infectious diseases or noninfectious immunogenic antigens and can mimic opportonistic disease ...
... inflammatory syndromes (IRIS) present as unexpected event or paradoxical deterioration of inflammation. IRIS is correlated to a variety of infectious diseases or noninfectious immunogenic antigens and can mimic opportonistic disease ...
Contents
1 | |
5 | |
85 | |
121 | |
Bacteria and Autoimmunity | 319 |
Parasites and Autoimmunity | 437 |
Infection and Diseases | 471 |
Subject Index | 741 |
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Infection and Autoimmunity Yehuda Shoenfeld,Nancy Agmon-Levin,Noel Richard Rose,Y. Shoenfeld Limited preview - 2004 |
Common terms and phrases
activation acute agents animals anti antibodies antigens arthritis Arthritis Rheum associated autoantibodies autoimmune disease bacterial binding blood cause cells chronic Clin clinical clones common complex controls cross-reactive cytokines damage demonstrated detected determined diabetes effects epitope et al evidence experimental expression factor frequency function gene genetic heart hepatitis host human immune response Immunol important increased individuals induced infection inflammatory initial involved lead levels liver lymphocytes major mechanisms mice molecular mimicry molecules multiple sclerosis myocarditis myosin Nature normal observed occur pathogenesis patients peptide peripheral persistent possible present production protein pylori reactive recent receptor recognized reported rheumatic fever risk role sequence serum severe showed shown similar specific spreading stimulation suggested syndrome synovial fluid T-cell therapy thyroid tion tissue treatment trigger type 1 diabetes vaccine vasculitis viral viral infection virus viruses
Popular passages
Page 147 - Navarro for their help in preparing the manuscript. This work was supported in part by CONACyT, Mexico and Fundacion RJ Zevada.
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Page 287 - Family study of the major histocompatibility complex in patients with systemic lupus erythematosus: importance of null alleles of C4A and C4B in determining disease susceptibility.
Page 147 - Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev 2001;182:18-32.
Page 283 - Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome Iq in African-American pedigrees. Proc Natl Acad Sci USA 1998:95(25): 14869-14874.
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Page 607 - A randomized trial comparing intravenous immune globulin and plasma exchange in Guillain-Barre syndrome.
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Page 245 - BURGESS, JA : High frequency of diabetes mellitus in young adults with congenital rubella.