Infection and AutoimmunityYehuda Shoenfeld, Nancy Agmon-Levin, Noel R. Rose Infection and Autoimmunity encompasses the different mechanisms involved in the infection-autoimmunity association/induction. Special attention is given to heat shock proteins (HSPs) and to transgenic mouse models to better understand infection-induced autoimmunity. Organized into six parts, this book first discusses the mechanisms of autoimmune induction by infection. Some chapters follow discussing the vaccination and vaccines, including the controversial issue of vaccine-autoimmunity relationship. Other chapters elucidate the relationship of bacteria and parasites to autoimmunity. Lastly, the aspects of infections and diseases are described. This reference material will help readers gain a deeper insight into the important etiological aspects of autoimmunity.
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From inside the book
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Page 14
... cell populations can be pathogenic. EAE has been induced in different ... responses to the PLP peptide. It is important to note that the wildtype ... cell-mediated autoimmune process that persists after the virus has been cleared. In ...
... cell populations can be pathogenic. EAE has been induced in different ... responses to the PLP peptide. It is important to note that the wildtype ... cell-mediated autoimmune process that persists after the virus has been cleared. In ...
Page 15
... CELL RECOGNITION A large number of studies have now demonstrated TCR ... responses to viral pathogens in vivo, as shown in a murine model where CD8 T ... cell population (30% of all CD8 T cells) when mice that had previously encountered ...
... CELL RECOGNITION A large number of studies have now demonstrated TCR ... responses to viral pathogens in vivo, as shown in a murine model where CD8 T ... cell population (30% of all CD8 T cells) when mice that had previously encountered ...
Page 19
... response induced by immunization with a single peptide antigen or a multi-determinant antigen [1–3]. The new T cell and/or antibody responses are directed to different epitopes either within the same antigen as that used for ...
... response induced by immunization with a single peptide antigen or a multi-determinant antigen [1–3]. The new T cell and/or antibody responses are directed to different epitopes either within the same antigen as that used for ...
Page 20
... cell response "Unless specified, all epitopes mentioned in Table 2 refer to T cell responses. The abbreviations are given in the order of their appearance in Table 2. MBP - Myelin basic protein; PLP – Proteolipid protein, TMEV ...
... cell response "Unless specified, all epitopes mentioned in Table 2 refer to T cell responses. The abbreviations are given in the order of their appearance in Table 2. MBP - Myelin basic protein; PLP – Proteolipid protein, TMEV ...
Page 21
... cell response to GAD65, Carboxy- [35] diabetic (NOD) mouse peptidase H, Insulin, and HSP65 NOD mice Spontaneous T cell and antibody response to [36] GAD65/67, Peripherin, Carboxypeptidase H, and HSP60 Adjuvant-induced arthritis Lewis ...
... cell response to GAD65, Carboxy- [35] diabetic (NOD) mouse peptidase H, Insulin, and HSP65 NOD mice Spontaneous T cell and antibody response to [36] GAD65/67, Peripherin, Carboxypeptidase H, and HSP60 Adjuvant-induced arthritis Lewis ...
Contents
1 | |
5 | |
85 | |
121 | |
Bacteria and Autoimmunity | 319 |
Parasites and Autoimmunity | 437 |
Infection and Diseases | 471 |
Subject Index | 741 |
Other editions - View all
Infection and Autoimmunity Yehuda Shoenfeld,Nancy Agmon-Levin,Noel Richard Rose,Y. Shoenfeld Limited preview - 2004 |
Common terms and phrases
activation acute agents animals anti antibodies antigens arthritis Arthritis Rheum associated autoantibodies autoimmune disease bacterial binding blood cause cells chronic Clin clinical clones common complex controls cross-reactive cytokines damage demonstrated detected determined diabetes effects epitope et al evidence experimental expression factor frequency function gene genetic heart hepatitis host human immune response Immunol important increased individuals induced infection inflammatory initial involved lead levels liver lymphocytes major mechanisms mice molecular mimicry molecules multiple sclerosis myocarditis myosin Nature normal observed occur pathogenesis patients peptide peripheral persistent possible present production protein pylori reactive recent receptor recognized reported rheumatic fever risk role sequence serum severe showed shown similar specific spreading stimulation suggested syndrome synovial fluid T-cell therapy thyroid tion tissue treatment trigger type 1 diabetes vaccine vasculitis viral viral infection virus viruses
Popular passages
Page 147 - Navarro for their help in preparing the manuscript. This work was supported in part by CONACyT, Mexico and Fundacion RJ Zevada.
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Page 287 - Family study of the major histocompatibility complex in patients with systemic lupus erythematosus: importance of null alleles of C4A and C4B in determining disease susceptibility.
Page 147 - Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev 2001;182:18-32.
Page 283 - Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome Iq in African-American pedigrees. Proc Natl Acad Sci USA 1998:95(25): 14869-14874.
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Page 607 - A randomized trial comparing intravenous immune globulin and plasma exchange in Guillain-Barre syndrome.
Page 529 - Jerne NK, Towards a network theory of the immune system.
Page 245 - BURGESS, JA : High frequency of diabetes mellitus in young adults with congenital rubella.