Infection and AutoimmunityYehuda Shoenfeld, Nancy Agmon-Levin, Noel R. Rose Infection and Autoimmunity encompasses the different mechanisms involved in the infection-autoimmunity association/induction. Special attention is given to heat shock proteins (HSPs) and to transgenic mouse models to better understand infection-induced autoimmunity. Organized into six parts, this book first discusses the mechanisms of autoimmune induction by infection. Some chapters follow discussing the vaccination and vaccines, including the controversial issue of vaccine-autoimmunity relationship. Other chapters elucidate the relationship of bacteria and parasites to autoimmunity. Lastly, the aspects of infections and diseases are described. This reference material will help readers gain a deeper insight into the important etiological aspects of autoimmunity.
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From inside the book
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Page 22
... associated epitopes. Unexpectedly, mice treated with intact anti-B7.1 antibody [10] or antiCTLA-4 antibody [12] during ongoing disease suffered from exacerbated relapsing disease and revealed enhanced epitope spreading. However, the ...
... associated epitopes. Unexpectedly, mice treated with intact anti-B7.1 antibody [10] or antiCTLA-4 antibody [12] during ongoing disease suffered from exacerbated relapsing disease and revealed enhanced epitope spreading. However, the ...
Page 46
... ASSOCIATED WITH SEQUENCE HOMOLOGY Molecular mimicry describes a situation whereby a foreign antigen can initiate an immune response in which a T or B cell component cross-recognizes self. The previous concept for the antigen specificity ...
... ASSOCIATED WITH SEQUENCE HOMOLOGY Molecular mimicry describes a situation whereby a foreign antigen can initiate an immune response in which a T or B cell component cross-recognizes self. The previous concept for the antigen specificity ...
Page 69
... associated with monoclonal Ig in the serum and urine or cases terminating in lymphoplasmocytoid leukaemia or lymphoma. Less than half of the B cell-derived non-Hodgkin's lymphomas are CD5+ [27]. The marker is mainly found on B cell ...
... associated with monoclonal Ig in the serum and urine or cases terminating in lymphoplasmocytoid leukaemia or lymphoma. Less than half of the B cell-derived non-Hodgkin's lymphomas are CD5+ [27]. The marker is mainly found on B cell ...
Page 77
... associated with thrombotic events, and therefore suspected to be pathogenic [27]. There is increasing evidence that AECA are associated with various viral infections. The autoAb have thus been reported in nephropathia epidemica, one of ...
... associated with thrombotic events, and therefore suspected to be pathogenic [27]. There is increasing evidence that AECA are associated with various viral infections. The autoAb have thus been reported in nephropathia epidemica, one of ...
Page 79
... associated with AECA are plenty, it is tempting to speculate on a role for these infectionrelated autoAb in the ... associated disease, 19 bands ranging from 15 to 200 kDa were identified by van der Zee et al [62] using WB, and Ab ...
... associated with AECA are plenty, it is tempting to speculate on a role for these infectionrelated autoAb in the ... associated disease, 19 bands ranging from 15 to 200 kDa were identified by van der Zee et al [62] using WB, and Ab ...
Contents
1 | |
5 | |
85 | |
121 | |
Bacteria and Autoimmunity | 319 |
Parasites and Autoimmunity | 437 |
Infection and Diseases | 471 |
Subject Index | 741 |
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Infection and Autoimmunity Yehuda Shoenfeld,Nancy Agmon-Levin,Noel Richard Rose,Y. Shoenfeld Limited preview - 2004 |
Common terms and phrases
activation acute agents animals anti antibodies antigens arthritis Arthritis Rheum associated autoantibodies autoimmune disease bacterial binding blood cause cells chronic Clin clinical clones common complex controls cross-reactive cytokines damage demonstrated detected determined diabetes effects epitope et al evidence experimental expression factor frequency function gene genetic heart hepatitis host human immune response Immunol important increased individuals induced infection inflammatory initial involved lead levels liver lymphocytes major mechanisms mice molecular mimicry molecules multiple sclerosis myocarditis myosin Nature normal observed occur pathogenesis patients peptide peripheral persistent possible present production protein pylori reactive recent receptor recognized reported rheumatic fever risk role sequence serum severe showed shown similar specific spreading stimulation suggested syndrome synovial fluid T-cell therapy thyroid tion tissue treatment trigger type 1 diabetes vaccine vasculitis viral viral infection virus viruses
Popular passages
Page 147 - Navarro for their help in preparing the manuscript. This work was supported in part by CONACyT, Mexico and Fundacion RJ Zevada.
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Page 245 - BURGESS, JA : High frequency of diabetes mellitus in young adults with congenital rubella.