COMMITTEE ON INTERSTATE AND FOREIGN COMMERCE OREN HARRIS, Arkansas, Chairman JOHN BELL WILLIAMS, Mississippl SAMUEL N. FRIEDEL, Maryland TORBERT H. MACDONALD, Massachusetts JOHN JARMAN, Oklahoma LEO W. O'BRIEN, New York JOHN E. MOSS, California JOHN D. DINGELL, Michigan JOE M. KILGORE, Texas PAUL G. ROGERS, Florida ROBERT W. HEMPHILL, South Carolina ANDREW STEVENSON KURT BORCHARDT JOHN B. BENNETT, Michigan W. E. WILLIAMSON, Clerk KENNETA J. PAINTER, Assistant Clerk Professional Sof SAM G. SPAL MARTIN W. CUNNINGHAM Aaron, Dr. Harold, medical adviser, Consumers Union.. Barr, Thomas, Certified Color Industry Committee: Blum, Dr. Harold F., National Cancer Institute and department of 406, 433, 465 Bullock, Carl R., Director, General Regulatory Division, Office of General Counsel, Department of Agriculture Byerly, T. C., Deputy Administrator, Farm Research, Department Clarkson, M. R., Associate Administrator, Agricultural Research Service, Department of Agriculture. Darby, Dr. William J., department of biochemistry, Vanderbilt Uni- De Eds, Dr. Floyd, Department of Agriculture, Western Utilization Delaney, Hon. James J., a Representative in Congress from the State Dunkelberger, H. E., Jr., on behalf of National Canners Association.. Edwards, Harold, vice president, National Hedth Federation... Flering, Hon. Arthur S., Sycretary of Health, Education, and Forsythe, Robert A.. Assistant Secretary for Legislation, Department of Health, Education, and Welfare.. Gerden, Paul, general counsel and secretary, Abbott Laboratories.. Haley, Hon. James A., a Representative în Congress from the State Heckman, Jerome, legal counsel, Society of the Plastics Industry, Holloway, Fuller, representing Toilet Goods Association.. Janss, Feter W., National Feed Ingredients Association. Kensler, Dr. Charles J., department of pharmacology, Boston Uni- 225 Kunilolm, John G., chairman, food packaging materials committee, 225 Levin, Dr. Morton L., Roswell Fark Memorial Institute.. Matson, Edward J., director of scientific administration, Abbott Mider, Dr. C. Burroughs, Associate Director in Charge of Research, 38, 406, 433, 465 III Miller, A. R., Director, Meat Inspection Division, Department of Miller, Dr. James A., McArdle Laboratory, University of Wisconsin.. Mulford, Kenneth E., chairman, food additives committee, Manu- Noone, J. A., technical adviser, National Agricultural Chemicals O'Donnell, Dr. Walter E., Sloan-Kettering Institute for Cancer Peterson, J. Hardin, special counsel, Florida Citrus Mutual.. Popham, W. L., Deputy Administrator, Crops Regulatory Programs, Riley, George D., legislative representative, AFL-CIO.. Schramm, Arthur T., representing Certified Color Industry Com mittee. Starkey, Ione Dennis, homemaker. Stewart, Dr. Harold L., National Cancer Institute.. Sullivan, Hon. Leonor Kretzer, a Representative in Congress from the Tannenbaum, Dr. Albert, Medical Research Institute, Michael Williams, Edward Brown, Pharmaceutical Manufacturers Associa- Ward, Justus C., Chief, Pesticide Regulations Branch, Plant Pest Worley, John K., general counsel, Pharmaceutical Manufacturers Zavon, Dr. M. R., Kettering Laboratory of Industrial Health... Additional information submitted for the record by Abbott Laboratories: Page 364 406, 433, 465 232 179 406, 433 158 136 364 145 136 229 406, 433, 465 109 406, 433, 465 253, 309 364 253 406, 433, 465 Letter from Paul Gerden, secretary and general counsel.. 607 570 Recommendations of.. 210 Scientific judgment in law and regulation, by Edward J. Matson, 219 Agriculture Department, letter from True D. Morse, Acting Secre tary. 391 American Feed Manufacturers Association, Inc., letter from W. E. 551 Animal Health Institute, letter from D. L. Bruner, executive secretary 559 Ansbacher-Siegle Corp., letter from J. W. Ingram, technical director.. 551 582 Carney, Dr. Thomas, safety of diethylstilbestrol Brown, Eric V., letter from... Central Soya Co., statement of Harold W. McMillen.. Certified Color Industry Committee, letter from Pickering, John H. attorney. Schramm, Arthur T.. chairman. Darby, Dr. William J. letter from.. 552 295 559 595 598 493 Doughboy Industries, Inc., letter from E. J. Cashman, president. 553 186 Health, Education, and Welfare Department: Estimate of cost of enforcement of proposed Color Additive 33 Explanation of principal features and purposes of proposed color 23 Letter from Hon. Arthur S. Flemming, Secretary, transmitting 15 Letter from George P. Larrick, Commissioner of Food and Drugs, CONTENTS Additional information submitted for the record by-Continued Petitions submitted with respect to packaging ingredients....... The role of certain chemical and physical agents in the causation Kansas State Board of Health: Letter from Evan Wright, director, food and drug division, Letters from Dr. Geoffrey Martin, executive secretary. Page 104 26 45 347 561, 562 565 247, 249 408 185 Kolmar Laboratories, Inc., letter from Lessing L. Kole, chairman of the board... Manufacturing Chemists' Association, Inc., letter from Kenneth E. Mulford, chairman, food additives committee, transmitting statement. Mider, Dr. George Burroughs, curriculum vitae.. Missouri, University of, letter from J. H. Longwell, director, division of agricultural sciences, transmitting statement.. National Association of Frozen Food Packers, letter from Lawrence S. 554 National Canners Association, letter from Carlos Campbell, executive secretary. National Association of Margarine Manufacturers, statement of 541 598 National Paper Box Manufacturers Association, Inc., letter from 184 National Starch and Chemical Corp., American Parboard Division, telegram from W. K. Grubman... 549 Newton Paper Co., letter from W. W. Newton, president.. 549 548 Nutritional Study Group of Cape Arthur, statement of Jane W. 539 Pfizer, Chas, & Co., letter from Allan J. Greene, administrative vice president. 593 Pharmacutical Manufacturers Association, letter from Edward Brown 588 President's Science Advisory Committee, report of panel on food additives.. Dee, R. F., manager, animal health products department. 587 583 Society of the Plastics Industry, Inc., suggested change in statutory language. 226 Sterling, Dr. Theodore D., publication decisions and their possible effects on inferences drawn from tests of significance, or vice versa.. Stewart, Dr. Harold L.: 472 Carcinogenicity and combination effects of hydrocarbons, table. 431 432 550 126 Tullock, Dr. Gordon, publication decisions and tests of significance, a comment.. 476 Walnut Grove Products Co., Inc., letter from Dick L. Jensen, general counsel.. 564 COLOR ADDITIVES TUESDAY, JANUARY 26, 1960 HOUSE OF REPRESENTATIVES, COMMITTEE ON INTERSTATE AND FOREIGN COMMERCE, Washington, D.C. The committee met, pursuant to call, at 10 a.m., in the committee room, New House Oflice Building, Hon. Oren Harris, chairman of the committee, presiding. The CHAIRMAN. The committee will come to order. The Chair observes we have a full house this morning. We regret we are unable to accommodate everyone with a seat. I hope, in view of the circumstances, that you will bear with us during these hearings. It will be our purpose to accommodate everyone we possibly can. If we can make more seats available during the day, we will certainly be glad to do so. The Committee on Interstate and Foreign Commerce is meeting this morning to begin hearings on two bills that would amend the Federal Food, Drug, and Cosmetic Act so as to authorize the use of suitable color additives in or on foods, drugs, and cosmetics, in accordance with regulations to be issued by the Secretary of Health, Education, and Welfare, prescribing the conditions, including maximum tolerances, under which such additives may be safely used. Under present law, the treatment of color additives differs radically as between the so-called coal tar colors and other colors. Coal tar colors must be tested by the Food and Drug Administration and certified as "harmless and suitable for use" before they can be used. Some colors originally listed as "harmless have been found, through advances in scientific knowledge, to produce injury when fed to animals in large amounts, and have been therefore removed from the certified list. The Federal Food, Drug and Cosmetic Act presently does not permit the establishment of tolerances for even safe amounts of coal tar colors. It will be recalled that a temporary exception was made last year when this committee approved an amendment to the act, which was passed by the Congress and became Public Law S6-2, permitting the temporary listing and certification of the color Citrus Red No. 2 for coloring mature oranges under tolerances found to be safe by the Secretary of the Department of Health, Education, and Welfare. I might say during the time we were considering this proposal we decided that it would be a temporary measure. This committee assured the Congress and the public that we would undertake to consider permanent legislation prior to the time of the termination of the temporary act. This meeting today and this consideration is pursuant to the promise made at that time. 1 |