Toxicological Profile for Atrazine |
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Page 22
... pure Duration / a Key to Species Frequency figure ( Strain ) ( Specific Route ) System NOAEL ( mg / kg / day ) ... pure Cooper et al . 2000 97.1 % pure ( 43 % decrease in body weight gain ) Cooper et al . 2000 97.1 % pure Cooper et al ...
... pure Duration / a Key to Species Frequency figure ( Strain ) ( Specific Route ) System NOAEL ( mg / kg / day ) ... pure Cooper et al . 2000 97.1 % pure ( 43 % decrease in body weight gain ) Cooper et al . 2000 97.1 % pure Cooper et al ...
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... pure ( Sprague- Dawley ) ( GW ) 56 Rat 28d 50 ( Fischer - 344 ) 1x / d ( GW ) Aso et al . 2000 98.7 % pure Aso et al . 2000 ( disrupted estrus cycle ; Cooper et al . 1996 altered serum estradiol and progesterone levels ) 59 Rat 1x / d ...
... pure ( Sprague- Dawley ) ( GW ) 56 Rat 28d 50 ( Fischer - 344 ) 1x / d ( GW ) Aso et al . 2000 98.7 % pure Aso et al . 2000 ( disrupted estrus cycle ; Cooper et al . 1996 altered serum estradiol and progesterone levels ) 59 Rat 1x / d ...
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... pure Exposure / Table 3-1 . Levels of Significant Exposure to Atrazine LOAEL Oral ( continued ) a Duration / Key to ... pure Wetzel et al . 1994 97 % pure 6.9 ( increased length of estrus ) 3. HEALTH EFFECTS 2 ( ovarian cysts ...
... pure Exposure / Table 3-1 . Levels of Significant Exposure to Atrazine LOAEL Oral ( continued ) a Duration / Key to ... pure Wetzel et al . 1994 97 % pure 6.9 ( increased length of estrus ) 3. HEALTH EFFECTS 2 ( ovarian cysts ...
Contents
CHEMICAL AND PHYSICAL INFORMATION | 4 |
RELEVANCE TO PUBLIC HEALTH | 11 |
HEALTH EFFECTS | 17 |
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alterations animals atrazine concentrations atrazine exposure atrazine in humans ATSDR Bd Wt biomarkers body weight gain carcinogenicity Catenacci Cooper Ćurić Dawley dealkylation decreased body weight dermal exposure detected developmental effects diet dose drinking water effects of atrazine Eldridge Endocr endocrine Environ environmental estradiol estrogen estrus cycle excretion exposure to atrazine Forward mutation gavage genotoxicity gestational days Gojmerac groundwater hazardous HEALTH EFFECTS Hepatic herbicide HUMAN EXPOSURE increased Infurna Less Serious mg/kg/day levels of atrazine Levels of Significant liver LOAEL located regarding Long-Evans luteinizing hormone male metabolites mg/kg mg/kg/day atrazine Minimal Risk Level mutation no-observed-adverse-effect level observed offspring Oral continued oral exposure pesticides pigs pituitary plasma progesterone prolactin prostate pure rats administered rats exposed Reference Chemical Form reproductive effects samples senescence Significant Exposure soil Sprague Sprague-Dawley Sprague-Dawley rats studies were located substance System NOAEL mg/kg/day Timchalk tissue toxicity Toxicol toxicological triazine urine vitro Wetzel Wistar rats µg/L BNA