Toxicological Profile for Atrazine |
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Page 70
... phase II metabolism of atrazine probably proceeds via glutathione conjugation and conversion to mercapturic acids in the kidneys before excretion . In vitro studies using microsomal preparations from liver and other tissues of humans ...
... phase II metabolism of atrazine probably proceeds via glutathione conjugation and conversion to mercapturic acids in the kidneys before excretion . In vitro studies using microsomal preparations from liver and other tissues of humans ...
Page 71
... phase II metabolism of atrazine through glutathione conjugation and mercapturic acid formation . While there are many similarities between and within species in phase I and phase II metabolism of atrazine , differences have also been ...
... phase II metabolism of atrazine through glutathione conjugation and mercapturic acid formation . While there are many similarities between and within species in phase I and phase II metabolism of atrazine , differences have also been ...
Page 146
... phase columns . In the latter case , one combined solid phase columns consisted of 66.6 % C - 18 silica - bonded phase and 33.3 % phenyl silica - bonded phase ( Benfenati et al . 1990 ) . Subsequent analysis of atrazine - containing ...
... phase columns . In the latter case , one combined solid phase columns consisted of 66.6 % C - 18 silica - bonded phase and 33.3 % phenyl silica - bonded phase ( Benfenati et al . 1990 ) . Subsequent analysis of atrazine - containing ...
Contents
CHEMICAL AND PHYSICAL INFORMATION | 4 |
RELEVANCE TO PUBLIC HEALTH | 11 |
HEALTH EFFECTS | 17 |
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alterations animals atrazine concentrations atrazine exposure atrazine in humans ATSDR Bd Wt biomarkers body weight gain carcinogenicity Catenacci Cooper Ćurić Dawley dealkylation decreased body weight dermal exposure detected developmental effects diet dose drinking water effects of atrazine Eldridge Endocr endocrine Environ environmental estradiol estrogen estrus cycle excretion exposure to atrazine Forward mutation gavage genotoxicity gestational days Gojmerac groundwater hazardous HEALTH EFFECTS Hepatic herbicide HUMAN EXPOSURE increased Infurna Less Serious mg/kg/day levels of atrazine Levels of Significant liver LOAEL located regarding Long-Evans luteinizing hormone male metabolites mg/kg mg/kg/day atrazine Minimal Risk Level mutation no-observed-adverse-effect level observed offspring Oral continued oral exposure pesticides pigs pituitary plasma progesterone prolactin prostate pure rats administered rats exposed Reference Chemical Form reproductive effects samples senescence Significant Exposure soil Sprague Sprague-Dawley Sprague-Dawley rats studies were located substance System NOAEL mg/kg/day Timchalk tissue toxicity Toxicol toxicological triazine urine vitro Wetzel Wistar rats µg/L BNA