Toxicological Profile for Atrazine |
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Page 69
... Metabolism Atrazine is extensively and rapidly metabolized as indicated by plasma levels of atrazine and the relative amounts of metabolites and parent compound in the urine within 8-24 hours after exposure . Plasma levels of 1C from ...
... Metabolism Atrazine is extensively and rapidly metabolized as indicated by plasma levels of atrazine and the relative amounts of metabolites and parent compound in the urine within 8-24 hours after exposure . Plasma levels of 1C from ...
Page 70
... metabolites in human and rat urine indicates that phase II metabolism of atrazine probably proceeds via glutathione ... metabolites recovered in the phase II portion . It was also noted 3. HEALTH EFFECTS that , in this in vitro system ...
... metabolites in human and rat urine indicates that phase II metabolism of atrazine probably proceeds via glutathione ... metabolites recovered in the phase II portion . It was also noted 3. HEALTH EFFECTS that , in this in vitro system ...
Page 97
... metabolites and parent compound in the urine within 8-24 hours after exposure . Plasma levels of 1C from radiolabeled atrazine have been shown to peak at 8-10 hours postexposure in rats , and the rate of clearance half - life has been ...
... metabolites and parent compound in the urine within 8-24 hours after exposure . Plasma levels of 1C from radiolabeled atrazine have been shown to peak at 8-10 hours postexposure in rats , and the rate of clearance half - life has been ...
Contents
CHEMICAL AND PHYSICAL INFORMATION | 4 |
RELEVANCE TO PUBLIC HEALTH | 11 |
HEALTH EFFECTS | 17 |
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alterations animals atrazine concentrations atrazine exposure atrazine in humans ATSDR Bd Wt biomarkers body weight gain carcinogenicity Catenacci Cooper Ćurić Dawley dealkylation decreased body weight dermal exposure detected developmental effects diet dose drinking water effects of atrazine Eldridge Endocr endocrine Environ environmental estradiol estrogen estrus cycle excretion exposure to atrazine Forward mutation gavage genotoxicity gestational days Gojmerac groundwater hazardous HEALTH EFFECTS Hepatic herbicide HUMAN EXPOSURE increased Infurna Less Serious mg/kg/day levels of atrazine Levels of Significant liver LOAEL located regarding Long-Evans luteinizing hormone male metabolites mg/kg mg/kg/day atrazine Minimal Risk Level mutation no-observed-adverse-effect level observed offspring Oral continued oral exposure pesticides pigs pituitary plasma progesterone prolactin prostate pure rats administered rats exposed Reference Chemical Form reproductive effects samples senescence Significant Exposure soil Sprague Sprague-Dawley Sprague-Dawley rats studies were located substance System NOAEL mg/kg/day Timchalk tissue toxicity Toxicol toxicological triazine urine vitro Wetzel Wistar rats µg/L BNA