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sively with the Bulgarian bacillus can be used. In practice, however, it is useful to associate with it another lactic microbe, known as the paralactic bacillus, as the latter, although producing less lactic acid than the Bulgarian. bacillus, does not break up the fats and gives the curdled milk a very pleasant flavour.

As it is undesirable to absorb too much fatty matter, it is necessary to prepare curdled milk for regular use from skimmed milk. After the milk has been boiled and rapidly cooled, pure cultures of the lactic microbes are sown in it, in sufficient quantities to prevent the germination of spores already in the milk and not destroyed in the process of boiling. The fermentation lasts a number of hours, varying according to the temperature, and finally produces a sour curdled milk, pleasant to the taste and active in preventing intestinal putrefaction. This milk, taken daily in quantities of from 300 to 500 cubic centimetres, controls the action of the intestine, and stimulates the kidneys favourably. It can therefore be recommended in many cases of disorder of the digestive apparatus, of the kidneys, and in several skin diseases.

The Bulgarian bacillus taken from yahourth or from soured milk, prepared from pure cultures of lactic microbes, can live in warm temperatures, and, as has been shown by Dr. Cohendy, is able to take its place in the intestinal flora of man.

Soured milk, prepared according to the receipt which I have given, has been analysed by M. Fouard, an assistant at the Pasteur Institute. When it was ready to be taken, M. Fouard found in it about 10 grammes of lactic acid per litre. Moreover, a large proportion (nearly 38 per cent.) of the casein had been rendered soluble during the fer1 Soured milk can be taken at any time of the day, with or in between meals.

mentation, which shows that its albuminous matter is prepared for digestion much as in kephir. Of the phosphate of lime (which is the chief mineral substance of milk) 68 per cent. was rendered soluble during the fermentation. These facts all confirm the utility of the soured milk prepared from pure cultures of lactic bacteria.

Those persons who, from some reason or other, cannot take milk, may swallow the bacilli in a pure culture without milk. However, as the microbes need sugar to produce lactic acid, it is necessary to take with them a certain quantity of sweet food (jam, sweet-meats, and especially beetroot).

The Bulgarian bacillus produces lactic acid not only from milk sugar, but also from many other sugars, for instance, cane sugar, maltose, levulose and especially glucose.

Cultures of the bacillus can be made not only in milk, but in vegetable broths, or broths of animal peptone to which sugar has been added. The cultures can be taken in a dry form (powders or tabloids), or in the liquid in which the bacilli had themselves been developed.

A reader who has little knowledge of such matters may be surprised by my recommendation to absorb large quantities of microbes, as the general belief is that microbes are all harmful. This belief, however, is erroneous. There are many useful microbes, amongst which the lactic bacilli have an honourable place. Moreover, the attempt has already been made to cure certain diseases by the administration of cultures of bacteria. M. Brudzinsky1 has used cultures of lactic microbes in certain intestinal diseases of infants, whilst Dr. Tissier has used them in similar affections of infants and adults.

1 Jahrbuch für Kinderheilkunde, N. F. 12 Ergansungsheft, 1900. 2 Annales de l'Institut Pasteur, 1905, p. 295; Tribune médicale, Feb. 24th, 1906.

From the general point of view of this book, the course recommended consists of the absorption either of soured milk prepared by a group of lactic bacteria, or of pure cultures of the Bulgarian bacillus, but in each case taking at the same time a certain quantity of milk sugar or saccharose.

For more than eight years I took, as a regular part of my diet, soured milk at first prepared from boiled milk, inoculated with a lactic leaven. Since then, I have changed the method of preparation and have adopted finally the pure cultures which I have been describing. I am very well pleased with the result, and I think that my experiment has gone on long enough to justify my view. Several of my friends, some of whom suffered from maladies of the intestine or kidneys, have followed my example, and have been well satisfied. I think, therefore, that lactic bacteria can render a great service in the fight against intestinal putrefaction.

If it be true that our precocious and unhappy old age is due to poisoning of the tissues (the greater part of the poison coming from the large intestine inhabited by numberless microbes), it is clear that agents which arrest intestinal putrefaction must at the same time postpone and ameliorate old age. This theoretical view is confirmed by the collection of facts regarding races which live chiefly on soured milk, and amongst which great ages are common. However, in a question so important, the theory must be tested by direct observations. For this purpose the numerous infirmaries for old people should be taken advantage of, and systematic investigations should be made on the relation of intestinal microbes to precocious old age, and on the influence of diets which prevent intestinal putrefaction in prolonging life and maintaining the forces of the body. It can only be in the future, near or remote, that we shall

obtain exact information upon what is one of the chief problems of humanity.

In the meantime, those who wish to preserve their intelligence as long as possible and to make their cycle of life as complete and as normal as is possible under present conditions, must depend on general sobriety and on habits conforming to the rules of rational hygiene.

PART V

PSYCHICAL RUDIMENTS IN MAN

I

RUDIMENTARY ORGANS IN MAN

Reply to critics who deny the simian origin of man-
Actual existence of rudimentary organs-Reductions in the
structure of the organs of sense in man-Atrophy of Jacob-
son's organ and of the Harderian gland in the human race

SEVERAL critics of The Nature of Man have protested against my theory of the simian origin of man. Some of these found my arguments unsatisfactory and unconvincing. Others have attacked generally my suggestion that some anthropoid had been suddenly transformed to a primitive human being.

It is true that so long as we have little palæontological evidence as to the actual descent of man, we cannot discuss the subject without the aid of hypotheses. I think, however, that recent additions to knowledge confirm the theory of the descent of man in a way that ought to influence the most resolute opponents. I have in mind chiefly the arguments supplied by the embryology of anthropoid apes, and by the investigation of their blood. None the less, there are still many authors who maintain their opposition. One of my critics, Dr. Jousset,' enumerates certain differences in the structure of the skeleton in man and apes, and concludes that these radically separate man from apes. 1 La nature humaine et la philosophie optimiste, Paris, 1904.

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