! Includes 15 percent allowance for indirect costs.

* Includes cancer research projects and cancer field investigation projects.

ESTIMATE FOR RESEARCH APPLICATIONS

Senator HILL. In this connection, last year the committee, in response to questions, elicited information that you estimated a need for $131,135,000 for research applications.

The committee requested a further report on your predictions of last year to see how accurate they stood up at the same time we asked for the report on next year's predictions.

The comparison table which has been supplied, and which will be included in the hearings, indicates that the actual approvals came to $150,970,000, or some $19 million more than predicted.

(The table referred to follows:)

Comparison table, fiscal year 1959 approvals: (a) Estimated Apr. 14, 1958; (b) actual 1959

[In thousands]

ANIMAL QUARTERS, HAMILTON, MONT.

Dr. SHANNON. I believe we discussed this before.

Perhaps I can just submit this.

Senator HILL. I think that was in that statement-that which is in that statement is already pretty well in the record.

I don't suppose there is anything to add to the animal quarters at Hamilton, Mont.?

Dr. SHANNON. No, sir. I believe we covered that.

Senator HILL. There is a $150,000 item here cited as "Research facilities construction and site acquisition."

RESEARCH FACILITIES CONSTRUCTION AND SITE ACQUISITION

STATEMENTS OF DR. JOSEPH E. SMADEL, ASSOCIATE DIRECTOR, NATIONAL INSTITUTES OF HEALTH; DR. JAMES A. SHANNON, DIRECTOR, NATIONAL INSTITUTES OF HEALTH; DR. LEROY E. BURNEY, SURGEON GENERAL; ROY L. HARLOW, CHIEF FINANCE OFFICER; AND JAMES F. KELLY, DEPARTMENT BUDGET OFFICER

APPROPRIATION ESTIMATE

"For the acquisition of a site for research facilities for large animals, including repairs, alterations, and construction of auxiliary facilities and temporary buildings, $150,000, to remain available until expended."

Dr. SMADEL. Mr. Chairman, the steadily increasing requirements for large animals for the investigative work of the NIH is part of a long trend, we believe. There are now available for work by the investigators in Bethesda some 1,500 large animals. And these include

horses, cows, sheep, goats, dogs, monkeys, and cats. We estimate that in 1961 this number will increase to something of the order of 2,000. And that within 5 years it will probably double, that is, to 3,000.

These animals are used for a number of purposes. In the first place, as the research work has gone into the chronic diseases, many of the animals, such as dogs, are kept for a good number of years. This means that more and more facilities are needed to hold these animals. There is increasing need for the larger animals such as horses and sheep to provide materials for the tissue culture.

NEED FOR LARGE ANIMAL FARM

And finally the facility that we have had available to us, a small 6-acre plot with some barn facilities is not adequate for our present needs, and it will not be adequate for our future needs. This facility has been very generously made available by a Mr. Casey, but the current lease has only 2 more years to run.

Over the period of the last several years, we have investigated the possibility of finding federally owned land in the general vicinity of Washington which might be used for a large animal farm. We have looked into the possibility of acquiring this from some of the other Government agencies and some of their installations in the neighborhood.

This has not seemed feasible.

It is our belief that it would be most desirable to acquire about a 400-acre farm in the western part of Montgomery County or in Frederick County that would be about 45 minutes by rapid transportation, which is now developing along Route 240, between the NIH and the farm.

These are our needs and our hopes.

LAND ACQUISITION

The $150,000 which was requested in the President's budget is primarily for the acquisition of land. The price of land, in this neighborhood is constantly going up, as you know. And we would like to get the land now before it skyrockets in price again.

This matter has been reviewed in the House, and the House allowed the request of $150,000 for

acquisition of the site outside the metropolitan area for large animals necessary for the research programs of the National Institutes of Health.

Senator HILL. Well, but you will need, will you not, additional funds for access roads, utilities, and for the building improvement.

Dr. SMADEL. We shall need those, sir. This will be a development over a period of years.

Dr. SHANNON. I might say, Mr. Chairman, that our main purpose right now is to get land. Quite apart from the price, it is our conviction that if we don't get this this year, or next year, we will never get it. Because the land just won't be available.

We prepared plans over the years. We have been trying to obtain a site for 3 years. These plans have been quite elaborate. Our approach this time was to ask for the least possible thing in order to get the budget item in and get the land, and then perhaps worry about this development at a later date.