Protooncogenes and Growth Factors in Steroid Hormone Induced Growth and DifferentiationProtooncogenes and Growth Factors in Steroid Hormone Induced Growth and Differentiation reviews current information regarding the complex nature of hormone-induced cell growth and differentiation. The contributors examine the emerging consensus that protooncogenes and growth factors mediate perhaps the most crucial steps leading to cell growth and differentiation. The primary objective of this book is to unite the status of current research related to protooncogenes and growth factors from diverse physiological systems to help readers gain a comprehensive understanding of the subject. Leading researchers have contributed outstanding chapters pertaining to steroid hormone-regulated cell growth and differentiation in normal and/or neoplastic tissues. This book will appeal to basic science researchers, clinicians, industrial researchers, and graduate students. |
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Contents
Chapter | 1 |
Chapter 3 | 31 |
Chapter 4 | 47 |
Nuclear Protooncogenes as Regulatory Genes and | 69 |
Chapter 6 | 87 |
Chapter 7 | 105 |
Chapter 11 | 117 |
Chapter 8 | 125 |
Common terms and phrases
Acad acid amplification autocrine binding Biol breast cancer breast cancer cells c-fos c-fos gene c-fos transcription c-jun c-myc c-myc expression c-myc gene c-myc mRNA cancer cell lines Cancer Res cell growth cell proliferation cellular Chem complex Dickson differentiation DNA-binding domain Eā effects EGF receptor EGFR Endocrinol Endocrinology endometrial carcinoma epidermal growth factor epithelium estradiol Estrogen induces estrogen receptor estrogen responsive extracellular fibroblasts function gene expression gene transcription glucocorticoid receptor growth factor receptor human breast cancer inhibition interactions jun-B Lippman mammary epithelial cells mammary tumor mechanism mediated modulate molecular mouse mRNA mRNA levels mutations Natl neu oncogene normal oncogene osteoblast osteocalcin overexpression pathway phosphorylation Proc progesterone receptor progestins promoter protooncogene rat uterus region regulatory role sequence serum response element specific Stancel steroid hormones steroid receptor stimulation studies synthesis tamoxifen TGF-a tissue transcription factors transcriptional activation transfected transforming growth factor uterus vitro vivo
Popular passages
Page 263 - JunFos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene. Cell.ā
References to this book
Endocrine Disruptors: Effects on Male and Female Reproductive Systems Rajesh K. Naz Limited preview - 1999 |