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109,210 118,890

Includes capital outlay as follows: 1964, $634 thousand; 1965, $310 thousand; 1966, $404 thousand.

Selected resources as of June 30 are as follows: Unpaid, undelivered orders. 1963. $129 thousand (1964 adjustments. -$34 thousand); 1964, $1,490 thousand; 1965, $1,490 thousand; 1966, $1,490 thousand.

and 2,201 in 1964. In addition, funds are pr general research support grants, and clinica

centers.

(b) Fellowships.-Approximately 484 awar supported in 1966 as compared to 486 in 196 in 1964.

(c) Training.-Funds for 1966 will provide to 107 schools of medicine, osteopathy, and pu for support of undergraduate training. Fund provide for 247 grants for graduate research a training including 1,131 traineeships. Comparal grants, and traineeships were 106, 257, and 1,1 and 104, 248, and 1,137 in 1964.

2. Direct operations-(a) Research.-Labora clinical research is conducted to aid in the und of the cardiovascular system and its diseases, phasis in therapeutic agents, diagnostic instru surgery, and clinical medicine.

(b) Collaborative studies.-This activity con supports epidemiological, geographical patho metrics research, and clinical trial studies to se edge of the causes and prevention of cardiova ease. Causal factors are sought both by inten of "natural experiments" in population group experimental modification of suspected factors drug, or other measures.

(c) Training activities.-Inservice training is for positions requiring unique combinations vascular training and experience.

Object Classification (in thousands of dollars)

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Total number of permanent positions..
Full-time equivalent of other positions.
Average number of all employees.
Average GS grade.
Average GS salary.

1. Grants (a) Research.-Approximately 2,054 grants Average salary of ungraded positions...__ will be supported in 1966 as compared to 2,061 in 1965,

1964 actual

Personnel Summary

5.243
136
48

5,427

651

253

90

174

137

1,018

830

6.223

943 634 101,048

117,428
-24

117,404

730
25

706

7.1

$7,024

$5,104

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(c) Training. During 1966 it is estimated that 317 grants will be awarded to accredited schools for the improvement of instruction. This compares to 313 and 311 grants in 1965 and 1964 respectively.

2. Direct operations (a) Research.-Clinical and laboratory research is conducted in the fields of arthritis, rheumatism, diabetes, and other metabolic disorders, as well as studies in the major disciplines including pharmacology, toxicology, physiology, biochemistry, nutrition, chemistry, pathology, endocrinology, physical biology, molecular biology, and chemical biology.

(b) Collaborative studies.-Collaborative studies are conducted cooperatively and under contract with individuals and institutions; also conducted are comprehensive programs in scientific communications, including preparation of abstracts on specific areas of research interests; broad programs in epidemiology, biometry, and geographic medicine and genetics.

Object Classification (in thousands of dollars)

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750-100-65

11,150

4,071

-30

958

300

16,479

65,205

1,008

66,213

138

766

67,117

68,723

-1,606

67,117

66,213
138

11.684

5,565

1,065
325

173

18,639 19,778

69,927 74,987

70,100

69,927 74,987

69,847

69,847

253

12,473

5,825

69,927
173

42,613
3,537

(b) Collaborative studies.-Contracts are programed in the areas of vaccine development and testing; research reagent development, production and distribution; and immunologic problems as they relate to tissue trans9,059 plantation. The increase in 1966 will provide for the expansion of long range testing to determine the cancer producing properties of virus vaccines.

55.209

Object Classification (in thousands of dollars)

1,122 358

74,987

74,987

74,987

74,987

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(b) Fellowships. An estimated 254 awards will be made in 1966 for postdoctoral, special and research career fellowships. This compares to 232 awards in 1965 and

267 in 1964.

(c) Training.-Funds for 1966 will provide approximately 181 grants to train individuals in allergy and immunology, tropical medicine, infectious diseases, parasitology, mycology and rickettsiology. This compares to 176 grants in 1965 and 162 in 1964.

2. Direct operations (a) Research. Laboratory, field and clinical research is conducted in the broad fields of

allergic, infectious and parasitic diseases. The increase in 1966 will provide for the expansion of studies in allergy and immunology and infectious diseases.

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(c) Training.-Approximately 240 graduate training grants will be supported in 1966 as compared to 243 in 1965 and 235 in 1964. These grants are made to training institutions to establish and improve programs to train teachers and clinical investigators in neurology, ophthalmology, and otology. Approximately 229 traineeships will be awarded to individuals for specialized postgraduate training in 1966 as compared to 239 in 1965 and 236 in 1964.

2. Direct operations (a) Research.-Research is being conducted on disorders of the brain, and spinal cord and peripheral nerves, such as epilepsy, multiple sclerosis, apoplexy, and Parkinson's disease; on neuromuscular disorders, such as muscular dystrophy; and on visual and other sensory disorders, such as glaucoma, uveitis, cataract, and hearing impairments.

(b) Collaborative studies.-These studies include the coordination and central service activities for the collaborative project on cerebral palsy, mental retardation, and other neurological and sensory disorders of childhood; the perinatal physiology studies using primates; and epidemiological, biometric, and international studies relating to cerebrovascular disease, speech and hearing disorders, and other disorders affecting the central nervous system.

(c) Training activities. Support is given for inservice training of qualified staff members in subjects related to neurological and other sensory disorders.

Object Classification (in thousands of dollars)

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1. Grants (a) Research.-Approximately 1,605 grants
will be supported in 1966 as compared to 1,602 in 1965
and 1,574 in 1964. In addition, funds are provided for Total number of permanent positions
general research support grants and clinical research center
grants.

Full-time equivalent of other positions..
Average number of all employees.
Average GS grade...

(b) Fellowships.-Approximately 155 fellowships will be supported in 1966 as compared to 151 in 1965 and 149 in 1964.

1964 actual

Personnel Summary

Average GS salary.

Average salary of ungraded positions.

4,659

101

114

4,874

459

352

62

190

35

844

1,012

4,960

924

376 67,897

1

81,984 -15 81,969

696

42

690

7.1 $7,024

$5,104

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