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CONTENTS
APPENDIXES
I. Second Report on the Oral Contraceptives, by the Advisory Commit- tee on Obstetrics and Gynecology, Food and Drug Adminis- tration, August 1, 1969...
II. First Report on the Oral Contraceptives, by the Advisory Commit-
tee on Obstetrics and Gynecology, Food and Drug Adminis-
tration, August 1, 1966...
III. Dear doctor letters:
IV. Articles:
Page
6839
6917
7017
Dated January 12, 1970, from Dr. Charles C. Edwards,
Acting Commissioner, Food and Drug Administration,
with accompanying revised labeling for oral contracep-
tives.
Dated June 28, 1968, from Dr. James L. Goddard, Com- missioner, Food and Drug Administration, with accom-
panying revised uniform labeling for oral contraceptives.. 7022
"Survey Links The Pill To Cancer," by Barbara Yuncker,
from the New York Post, February 14, 1970___.
"Editorial-The Pill Problem," from the New York
Times, January 17, 1970-
7026
7027
"Commonsense Advice on Contraceptives," from Family
Health, January 1970, pp. 36–38_.
"Controversy Over 'The Pill,'" by Bill Surface, from
Good Housekeeping, January 1970, pp. 64-65, 123–127_
"The Better Way-Why There is Growing Concern About
the Safety of "The Pill,' from Good Housekeeping,
January 1970, pp. 129–131_-
"Original Articles-Vascular Lesions in Women Taking
Oral Contraceptives," by N. S. Irey, M.D., W. C.
Manion, M.D., and H. B. Taylor, M.D., from Archives
of Pathology, Vol. 89, No. 1, January 1970, pp. 1-8----
"Researcher Predicts Ban On The Pill," by Barbara
Yuncker, from the New York Post, December 22, 1969,
p. 3
"Oral Contraception and Depression," from the British
Medical Journal, November 15, 1969, pp. 380–381...
"OCs Can Deeply Alter Glucose Metabolism," from OB-
GYN News, November 15, 1969, pp. 2, 46.-
"Why Would the U.S. Ban Cyclamates and Not The Pill?"
by Morton Mintz, from the St. Louis Globe-Democrat,
November 5, 1969, p. 5A...
"Chapter 7-Implications of Contraception-A. Meta-
bolic Effects of Oral Contraceptives," by Philip A. Corf-
man, M.D., from the Journal of Medical Education, Vol.
44, Part 2, No. 11, November 1969, pp. 64-68-
"Metabolic Effects of Oral Contraceptives," from The Lan-
cet, October 11, 1969, pp. 783–784_ -
7028
7031
7037
7042
7050
7051
7052
7054
7056
7060
"Family Planning and Public Policy: Who Is Misleading
Whom?" from Science, September 19, 1969, pp. 1203-
1204_.
7062
"Prevalence Rates of Uterine Cervical Carcinoma in situ
for Women Using the Diaphram or Contraceptive Oral
Steroids," by M. R. Melamed, M.D., L. G. Koss, M.D.,
B. J. Flehinger, Ph. D., R. P. Kelisky, Ph. D., and H.
Dubrow, M.D., from the British Medical Journal,
July 26, 1969, pp. 195-200___
7064
IV
IV. Articles-Continued
Whom?" by O. Harkavy, F. S. Jaffe, and S. M. Wishik,
from Science, July 25, 1969, pp. 367-373_.
"The Association of Mortality From Thromboembolic
Disorders and Oral Contraceptive Use," by D. G.
Seigel, Sc. D., reprinted from the Journal of Reproduc-
tive Medicine, July 1969, Vol. 3, No. 1, pp. 44–49.
"Population Policy for Americans: Is the Government
Being Misled?" by Judith Blake, Chairman, Dept. of
Demography, University of California, Berkeley, from
Science, May 2, 1969, pp. 522–529.
"Oral Contraceptives and Mortality Trends From Throm-
boembolism in the United States," by R. E. Markush,
M.D., M.P.H., and D. G. Seigel, S.D., reprinted from
American Journal of Public Health, Vol. 59, No. 3,
March 1969, pp. 418-434_.
"Pill Experts Perplexed By Data On Pap Smears," from
Medical World News, February 14, 1969, pp. 20-21.
"Oral Contraceptives: Government-Supported Programs
Are Questioned," by M. Mueller, from Science, Febru-
ary 7, 1969, pp. 553–555...
"Oral Contraceptives and Cerebrovascular Complications,'
by R. T. Bergeron, M.D., and E. H. Wood, M.D., re-
printed from Radiology, Vol. 92, No. 2, pp. 231–238, 258,
February 1969__.
"Editorial-Oral Contraceptives and Thromboembolic
Disease," by M. P. Vessey, M.B., B.S., from the American
Heart Journal, Vol. 77, No. 2, February 1969, pp. 153-
157..
The Pill: Press and Public at the Experts' Mercy-First
Part," by Morton Mintz, from Columbia Journalism
Review, Winter, 1968-1969, pp. 4–10 -
"The Pill: Press and Public at the Experts' Mercy-Second
Review, Spring, 1969, pp. 28-35.-
"Caution On The Pill," by Louis Lasagna, M.D., from SR,
November 2, 1968, pp. 64-69_
"Puerperal Thromboembolism in Relation to the Inhibition
of Lacation by Oestrogen Therapy," by T. N. A. Jeff-
coate, M.D., J. Miller, M.B., R. F. Roos, M.B., and V. R.
Tindall, M.D., from the British Medical Journal, Octo-
ber 5, 1968, pp. 19–25_
"Thrombosis and Inhibition of Lactation," from the British
Medical Journal, October 5, 1968, pp. 1-2...
"Effect of Oral Contraceptives on Depressive Mood
Changes and on Endometrial Monoamine Oxidase and
Phosphatases," by E. C. G. Grant, M.B., and J. Pryse-
Davies, M.D., from the British Medical Journal, Septem-
ber 28, 1968, pp. 777-780_.
"Oral Contraceptives and Thromboembolism," from the
British Medical Journal, April 27, 1968, pp. 187-188..
"Papers and Originals-Investigation of Deaths from Pul-
monary, Coronary, and Cerebral Thrombosis and Em-
bolism in Women of Child-Bearing Age," by W. H. W.
Inman, M.A., and M. P. Vessey, M.B., from the British
Medical Journal, April 27, 1968, pp. 193-199.
"Investigation of Relation Between Use of Oral Contra-
ceptives and Thromboembolic Disease," by M. P. Vessey,
M.B., and R. Doll, M.D., from the British Medical
Journal, April 27, 1968, pp. 199–205.
"Research-Biochemistry of the Pill Largely Unknown,"
from Chemical and Engineering News, March 27, 1967,
pp. 44-49
7074
7086
7092
7105
7122
7124
7127
7136
7140
7146
7154
7165
7176
7178
7185
7186
7198
7210
"Oral Contraceptives Safe, FDA Says," from the AMA
News, Vol. 9, No. 34, August 22, 1966, pp. 1, 6_ - - - -
7218
V
"Special Report Based On New Medical Evidence-Must
We Now Ban The Birth Control Pills?" from Good Page
Housekeeping, February 1966, pp. 67-68.
"One Noted Authority Says: 'Yes, I'll Still Prescribe The
Pills,'" by Dr. Alan F. Guttmacher, from Good House-
keeping, February 1966, pp. 68–70.
"How Does The Pill Work?" from Good Housekeeping,
February 1966, p. 70.
7219
7220
7223
"Are Birth Control Pills Safe?-Some Doctors Doubt That
The Drug Has Been Tested Well Enough for Possible
Side Effects," by Morton Mintz, from the Washington
Post, December 19, 1965, pp. El, E5--
"Birth-Control
Pills-Have They
Side-Effects?-An
Authoritative Answer to a Question Many Women Are
Asking," by E. J. DeCosta, M.D., from This Week Maga-
zine, July 12, 1964, p. 13..
V. Wright Committee Reports on Enovid by the Ad Hoc Com-
mittees for the Evaluation of a Possible Etiologic Relation With
Thromboembolic Conditions:
Dated August 4, 1963_
Dated September 12, 1963_
7224
7233
7235
7247
VI. Letter, dated February 26, 1970, to Subcommittee on Monopoly,
Select Committee on Small Business, U.S. Senate, from Education
and Public Welfare Division, Legislative Reference Service, Library
of Congress, re study of pharmaceutical advertising and critical
reactions regarding oral contraceptives in selected medical journals. 7254
VII. Letter, dated March 4, 1970, to Subcommittee on Monopoly, Select
Committee on Small Business, U.S. Senate, from Education and
Public Welfare Division, Legislative Reference Service, Library of
Congress, re articles discussing side effects of oral contraceptives. 7257
VIII. Planned Parenthood-World Population news release, "Mass Oral
Contraceptive Study Findings Released," June 1965-
IX. Medical and Pharmaceutical Information Bureau of Science Public
Relations, Inc. news release, "Oral Contraceptive Not Cause of
Thromboembolisms: Dr. Guttmacher," February 17, 1966.-
X. Washington Women's Liberation Statement on Birth Control Pills
with accompanying questionnaire_.
XI. Letter, dated March 10, 1970, to Benjamin Gordon, from Senator
Bob Dole, with accompanying articles on oral contraceptives:
"Health-IUD Hazards," by Morton Mintz, from the
Washington Post, March 5, 1970--
7263
7282
7283
7296
"Medical Report-'Pill' Warning to Set a Precedent," by
Judith Randal, from The Evening Star, March 8, 1970. 7297
"'Pill' Sales and Stocks Cooled by Controversy," by Bailey
Morris, from The Evening Star, March 8, 1970-
XII. Letter, dated January 30, 1963, to G. D. Searle & Co., from Arthur
Ruskin, M.D., Acting Medical Director, IND, and Haimo Trees,
M.D., Division of New Drugs, re Enovid medication and in-
creased blood clotting_
7298
7300
7301
XIII. Statement of John R. Rague, Executive Director, Association for
Voluntary Sterilization, Inc., re voluntary contraceptive steriliza-
tion as a major method of birth control.
XIV. Excerpts from testimony in the case of Raymond Black vs. G. D.
Searle & Co‒‒‒‒.
7306
XV. Memorandum dated May 11, 1960, from W. H. Kessenich, Bureau
of Medicine, to George P. Larrick, Commissioner of Food and
Drugs, re Enovid tablets, NDA 10-976___
7322
NOTE.-Appendixes are to Parts 15 and 16 (Oral Contraceptives-Volumes
1 and 2).