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animal which inflicted the bite was really mad. But the cases in which satisfactory experimental proof has been obtained are considered separately in the statistics of the Pasteur Institute. Thus, in the year 1901, 171 persons were treated who had been bitten by animals proved to be rabid, and among these not a single death occurred.

INDEX

Acquired immunity, 73

Breathing exercises, 176
Alcohol as an antiseptic, 41

Bubonic plague, 89
Amebic dysentery, 140

- bacillus of, 101
Anopheles, 235

– in Philippine Islands, 102
Anthrax, 23

- mortality from, 94-98
Antiseptic, definition of, 29

- period of incubation, 105
— surgery, 269

- prevention of, 108
Antiseptics, 41

- protective inoculations, 107
Antitoxin of diphtheria, 198
Antitoxins, 82

Carbolic acid as a disinfectant, 59
Aseptic surgery, 269

Caustic alkalies as disinfectants, 58
Asiatic cholera, 10

Channels of infection, 14
Attenuation of virulence, 64, 78

Chicken-pox, 221

Children, susceptibility of, 25
Bacilli, 10

Chloride of lime, 60
Bacillus of bubonic plague, 101 Chlorin as a germicide, 56,
-- diphtheria, 193

Chlorinated lime, 60
- influenza, 200

Cholera, 110
- leprosy, 182

- germs of, 120
- tetanus, 273

– in America, 111-116
- tuberculosis, 160

– origin of epidemics, 117, 118
- typhoid fever, 136

– predisposing causes, 118
Bacteria, 37

- protective inoculations, 124
- multiplication of, ii

- recent epidemics, 116
- structure of, 13

Cholera germ, description of, 120
- spores of, 12

– destruction of, 118, 122
Bichloride of mercury, 61

- discovery of, 120
Black death, 91, 93

- infection by, 118, 119
Bleaching powder, 60

Cholera infantum, 140
Blood-poisoning, 20

Citric acid as a germicide, 57
- germs of, 265–269

Climate in treatment of consumption,
Blood serum, germicidal action of, 177
68, 268

Clothing, disinfection of, 47
19

289

Dry heat as a disinfectant, 44
Dust, infection through, 16, 51
Dysentery, 140
- mortality from, 141

Clothing, infection through, 18
Coal-tar products as germicides, 59
Cold, action of, on bacteria, 46
Colonies of bacteria, IT
Comma bacillus, 120
Contagion, definition of, 3
Corrosive sublimate as a disinfectant,

61
Creolin as a disinfectant, 60
Cresol as a disinfectant, 60
Culture experiments, 37
- fluids, 38
Cuspidors for consumptive patients,

171, 172

Ehrlich's side chain theory, 85
Electric light, germicidal action of, 49
Epidemics, termination of, 99
Eruptive fevers, 17
Erysipelas, germ of, 266, 267
Excreta, disinfection of, 47, 60

Famine fever, 151
Filth diseases, 103, 126
Flies, as carriers of infection, 18
Fomites, 3
Formaldehyd as a disinfectant, 54 ·
Fumigation, 53

German measles, 233
Glanders, 24

Deodorants, 30
Desiccation of bacteria, 46
Diphtheria, 191
- animals susceptible to, 192
- antitoxin of, 198
- bacillus of, 193
- disinfection in, 195
- mortality from, 194
- prevention of, 195
– propagation of, 191
Diphtheria bacillus, 193
– destruction of, 195
- discovery of, 192
- varieties of, 192
Disease germs, 8
- dates of discovery, 148
Disinfectant, definition of, 28
Disinfection, 28
— by gases, 51
- evidence of, 34
- in bubonic plague, 108
- in cholera, 122, 123
- of bed-linen, 60
- of clothing, 47
- of excreta, 47, 60
- of sick-room, 51-53, 174
- of sputa, 171
- tests of, 32

Heat, disinfection by, 43
Hospital gangrene, 19
Hydrophobia, 279
– mortality from, 282
- Pasteur's experiments, 283
- period of incubation, 279
- prevention of, 281

protective inoculations, 283–288
- susceptible animals, 280
- transmission of, 284

Immunity, acquired, 73
- due to alkalinity of blood, 67
– due to body temperature, 66
– natural, 63
Infection, definition of, 4, 7

- general remarks upon, 3
Influenza, 199
- bacillus of, 200
- bacillus, destruction of, 204
– complications of, 200
– epidemics of, 200-202

Influenza, incubation period, 202
– mortality from, 199, 200
– predisposing causes, 202
- prevention of, 203
Inoculation for smallpox, 76

Lepers, isolation of, 189
Leprosy, 181
- bacillus of, 182
- disinfection in, 190
– history of, 186
– in Great Britain, 187
– in India and China, 187
- in Norway, 188
– in United States, 189
- inoculation experiments, 182
– transmission of, 186
Leucocytes, phagocytic action of, 71
Lime as a disinfectant, 59
Lye as a disinfectant, 58
Lysol, 60

Micrococcus of erysipelas, 265, 267
- of pneumonia, 206
- of pneumonia, discovery of, 205
- of pneumonia, where found, 208
- of puerperal fever, 266
Micro-organisms, 8
Milk, antitoxins in, 82

– from tuberculous cows, 175
Mineral acids, as germicides, 57
Mortality of armies, 129, 143
Mosquitoes, infection by, 21
- malarial parasite in, 243
- transmission of yellow fever by,

255
Mucous membrane, infection through,

21

Natural immunity, 63

Oysters, infection by, 18

Malaria, 235
Malarial fevers, 234
— fevers, geographic distribution of,

245
- fevers, mortality from, 247
– fevers, period of incubation, 240
— fevers, prevention of, 249–251
– fevers, seasonal prevalence of, 246
- parasite, 237, 241
– parasite, discovery of, 234
- parasite, varieties of, 240-242
Measles, 228
- complications of, 230
- disinfection in, 230, 231
- mortality from, 229
- period of incubation, 228
- prevention of, 231
- second attacks, 233
Membranous croup, 194
Metchnikoff's theory, 72
Micrococci, 16

Pasteur Institute, statistics of, 287,

288
Period of incubation, 6
Phagocytosis, 71, 72
Plasmodium malariæ, 237
Pneumonia, 205
– epidemics of, 209
- in Chicago, 207
– in United States, 206
– mortality from, 207
- predisposing causes, 206
- prevention of, 210
Pocket flasks for consumptives, 172
Potash as a germicide, 58
Protective inoculations, 75-78
– inoculations in bubonic plague,

107, 108
- inoculations in cholera, 124
- inoculations in typhoid fever, 139
Protophyta, 10
Protozoa, 10
Ptomaines, 30

1 – of tetanus bacillus, 273, 274

- resistance to heat, 44
Sputum, disinfection of, 171
Staphylococcus pyogenes aureus, 265
Steam as a disinfectant, 44
Streptococcus pyogenes, 267
Summer complaint, 140
Sulphate of copper as a germicide, 62
- iron as a germicide, 29
Sulphur fumigation, 53, 54
Sulphurous acid as a germicide, 58
Sunlight as a disinfectant, 48
Susceptibility, individual, 25
– due to alcoholism, 68
— race, 23
Surra disease, 22

Puerperal fever, germ of, 266, 267
Pulmonary consumption, mortality

from, 160-162
Pure cultures, 38
Race susceptibility, 24
Rats as agents in spread of plague,

104
Kelapsing fever, 145
- epidemics of, 146, 147
- germ of, 148
– in United States, 147
– predisposing causes, 151
- prevention of, 152
Salt as an antiseptic, 41
Sanitoria in treatment of tubercu.

losis, 169
Saprophytes, 86, 267
Scarlet fever, 223
- history of, 223
--- how communicated, 223
- mortality from, 225
- prevention of, 226
Second attacks of infectious diseases,

73-74
Septicæmia, 19
Sewers, sanitary value of, 127
Ship fever, 157
Sick-room, disinfection of, 51
Skin, infection through, 21
Smallpox, 214
- disinfection in, 220
- duration of, 220
- germ of, 219
- history of, 214
- mortality from, 215
– second attacks of, 74
Snake poison, antitoxin of, 85
Soda as a germicide, 59
Spirilla, 10
Spirillum of cholera, 121
- of relapsing fever, 149
Spores, 12, 39

Tetanus, 272
- bacillus of, 273
-- mortality from, 276–278
— toxin, 273-275
Texas fever, 21
Thermal death-point of bacteria, 45
Ticks, infection by, 21
Tonsils, infection through, 15
Toy pistols, danger of, 276
Trichinosis, 19
Trismus neonatorum, 277
Tsetse-fly disease, 22
Tubercle bacillus, 160
- destruction of, 176
– discovery of, 159
- in milk, 175
Tubercular joint disease, 163
Tuberculosis, 159
- communication of, 159-163
– in Europe, 166
- in New York City, 161, 178
- influence of occupation, 165
- - race, 166
- mortality from, 160, 162
- of bowels, 163
- predisposing causes of, 164

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