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Proposed for separate transmittal: Appropriation...

28

1964 1965 estimate estimate

Total, Department of Defense-Civil..

Proceeds from the sale of game permits are used to carry out a program of fish and game conservation and

Operation and maintenance, general, Corps of EngineersCivil...

Flood control, hurricane and shore protection emergencies, Corps of Engineers-Civil..

Flood control, Mississippi River and tributaries, Corps of Engineers Civil........

Payments to States, Flood Control Act of 1954, Corps of Engineers-Civil.

Hydraulic mining in California, debris fund, Corps of Engineers-Civil.

Maintenance and operation of dams and other improvements
of navigable waters, Corps of Engineers-Civil..
Construction of power systems, Ryukyu Islands, Army-
Construction of water systems, Ryukyu Islands, Army.
Canal Zone Government: Capital outlay.
Thatcher Ferry Bridge: Panama Canal Company
Payment to claimants, disaster at Texas City, Tex., Army
Wildlife conservations, etc., military reservations, Army.
Wildlife conservation, etc., military reservations, Air Force.
Other...

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-14

14

30

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ANALYSIS OF UNEXPENDED BALANCES [In thousands of dollars]

Balance, start of 1963

Unobligated

2,394 42,494

12,082

1,545

1,614

3

154 4,000

123 2.043

1.626 4

14

68,096

5,169

30

4,513

-383

4,130

77,395

rehabilitation in cooperation with the Fish and Wildlife. Service (63 Stat. 759).

Object classification (in thousands of dollars)

11 Personnel compensation: Permanent positions..

12 Personnel benefits..

25

Other services..

26 Supplies and materials.

Total obligations..

Total number of permanent positions..
Average number of all employees..
Employees in permanent positions, end of year.
Employees in other positions, end of year.
Average GS grade..
Average GS salary.
Average salary of ungraded positions..

Total

4.285 211,589

24,530

16,217

1,614

5

154 18,000 123

5,966

2.721

4

14 9,009

294,230

10,000

4.534 27,555

19,764

51,853

Balance, start of 1964

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Personnel Summary

-3,270 41,912

356,081 65,535 319,902

1.456

24,681

2,850

Balance, start of 1965 Unobligated

4

1,828

154 7,500

1.333

868

22

14

5.510

25,002 -5,315 11,400

40,710

1963 actual

35,395

17

Total

28

0 4.0

$4,514 $4.326

146

5.403

202,764

28,424

3,253

11,941

1,828

154 10,100

5,511

982

31

15 9,408

279,814

10,000

1964 1965 estimate estimate

100 328,677

8129

30

0 4.0 $4,638

$4,326

1,828

Balance, start of 1966

Unobligated

154 7,500

678

868

17

14

11,059

5.368

27,502 -3,639 5,893

-5,315 38,763 -3,639

1,691

18

1

2

9

30

9,111

0

4.0 $4,784

$4,326

Total

5,563 217,107

31,700

1.403

11,701

1,828

154 7,900

5,087

982

31

15 13,279

296,750

10,000

5,368 31,002

6,837

43,207

349,958

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DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE

FOOD AND DRUG ADMINISTRATION

General and special funds:

SALARIES AND EXPENSES

For necessary expenses not otherwise provided for, of the Food and Drug Administration, including reporting and illustrating the results of investigations; purchase of chemicals, apparatus, and scientific equipment; payment in advance for special tests and analyses and adverse reaction reporting by contract; payment of fees, travel, and per diem in connection with studies of new developments pertinent to food and drug enforcement operations; compensation of informers; payment for publication of technical and informational materials in professional and trade journals; and rental of special purpose space in the District of Columbia or elsewhere; [$35,805,000] $39,500,000. (Federal Food, Drug, and Cosmetic Act, as amended (21 U.S.C. 301-392); the Tea Importation Act, as amended (21 U.S.C. 41-50); the Import Milk Act (21 U.S.C. 141-149); the Federal Caustic Poison Act (15 U.S.C. 401-411); the Filled Milk Act, as amended (21 U.S.C. 61-64); and the Federal Hazardous Substances Labeling Act (15 U.S.C. 401); Department of Health, Education, and Welfare Appropriation Act, 1964.)

Program and Financing (in thousands of dollars)

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and Drug Administration. This continues the program of increasing and strengthening the agency's resources to cope with increased responsibilities due to industrial, economic, technological and population growth. The 1965 increase specifically provides for additional resources to implement the Drug Amendments of 1962. Other major increases are to provide additional resources and competences for medical and other scientific activities of the agency.

1. Field inspections, investigations, and laboratory analyses.-Inspections of domestic plants, examinations of interstate and import shipments and special investigations are planned according to the relative incidence and seriousness of probable violations. About 100,000 establishments (manufacturing plants, warehouses, shippers) dealing in foods, drugs, devices, or cosmetics are subject to inspection. Retail establishments dealing in products received in interstate commerce are also subject to the prohibition against adulteration or misbranding. Samples are collected during inspections, and investigations and laboratory analyses are conducted to detect and identify adulteration.

2. Research and methodology.-Research is conducted to evaluate the components of foods, drugs, devices, cosmetics, and household products suspected of containing hazardous substances, and to appraise their efficacy, toxicity, and acute and long-range effects. Research is also performed to develop analytical methods for use in field analysis of inspectional samples and to develop food standards and pesticide, food additive, and color additive tolerances.

3. Compliance, consultation, and education.-Voluntary compliance with the law is promoted wherever possible, but legal action is taken when necessary. Legal proceedings include citations, seizures of illegal products, injunctions, and criminal prosecutions through the courts. Standards for foods, tolerances for poisonous substances in foods, and other regulations are promulgated. A program of consumer education is conducted. Liaison is maintained with, and assistance is given to, State and local food and drug agencies.

4. Medical evaluation.-Applications for new drugs to be marketed, or for modification of previously approved drugs, are evaluated and approved. The medical aspects of research and enforcement activities are coordinated. Labels for drugs and household products containing hazardous substances are evaluated for honesty of claims, sufficiency of information.

Workload is reflected in the following summary data:

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This appropriation consolidates all activities related to the planning, construction, and equipping of buildings and facilities for the Food and Drug Administration.

Since 1957, the Food and Drug Administration has been engaged in a program to improve and enlarge its field facilities. Improvements have been provided for 11 of the 18 FDA district offices of which all but 1 have through the leasing of facilities. been domaining 7 districts will be provided through direct

The
Federal construction.

space

FDA has also had a program to provide additional and facilities at headquarters. A new headquarters laboratory building (Federal office building No. 8) is now under construction and nearing completion. A special pharmacological animal laboratory is under construction

Personnel Summary

-1,918

1964 estimate

245 65 1,428

1,403

722

1,073

2,125

2,811

-207

1,797

1,918 4,608

1965 estimate

150

3,740 15 4,095

8,000

3,025

11,025

BUILDINGS AND FACILITIES

For construction, alteration, and equipment, of facilities, including acquisition of sites, and planning, architectural, and engineering services, [$4,466,000 $11,025,000, to remain available until expended. (Department of Health, Education, and Welfare Appropriation Act, 1964.)

-142

4,466 11,025

1963 actual

Note. Estimate is for activities previously carried under "Pharmacological animal laboratory building" and "Salaries and expenses.' The amounts obligated in 1963 and part of 1964 are shown in the schedule as comparative transfers.

Deduct selected resources, start of year

15 3,061

2

27,638

3,076

3,210 24 2,696 3,164 89 7.7

$7,013

Analysis of 1965 financing

1 Selected resources as of June 30 are as follows: Unpaid undelivered orders, 1962, $1,470 thousand (1963 adjustment, $16 thousand); 1963, $1,279 thousand; 1964, $3,076 thousand; 1965, $6,101 thousand.

1964 estimate

Add selected resources, end of year

35,748

3,867

24 3,441 3,794 46 8.2 $7,703

6,101

Appropriation required, 1965

1965 estimate

150

3,740

7,135

39.737

6,101 11,025

4,102

24

3,848 4,009

55

8.2 $7,699

Appropriation required

to com

plete

315

4,774

5,089

at Beltsville, Md. In 1964 planning will be completed for the first major laboratory to be located on the Beltsville site. A special dog whelping facility will also be constructed at Beltsville to provide necessary dog colonies for the pharmacological-animal laboratory.

Steps taken to provide interim laboratory space until permanent facilities become available include the renova tion of building 197 at the Navy Yard in Washington and the retention of present laboratory space at Boston. New York, and Baltimore when operations at these locations are transferred to new facilities to be completed in

be transferred to these locations as the space becomes available. The program proposed for 1965 calls for:

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