Remington - Essentials of Pharmaceutics

Front Cover
Linda A. Felton
Pharmaceutical Press, 2013 - Medical - 784 pages
1 Review
Remington: Essentials of Pharmaceutics provides a concise yet detailed resource covering all aspects of pharmaceutics, from the scientific fundamentals to the dosage forms and drug delivery systems to drug product analyses. The pharmaceutics section in Remington: The Science and Practice of Pharmacy, which is the most commonly used and well respected section of the book, is presented here as a single volume, designed to be portable for laboratory and classroom use. This book focuses on the pharmaceutics aspects of pharmacy practice. The text pulls heavily from the Pharmaceutics and Pharmaceutical Dosage Forms sections. Various delivery systems and dosage forms are covered as well as parenterals, sterilization processes, and sterile compounding. One chapter addresses pharmaceutical excipients and another discusses pharmaceutical packaging. Pharmaceutical analysis, product characterization, quality control, stability, bioavailability, and dissolution are also covered. Fundamental scientific concepts including thermodynamics, ionic solutions and electrolyte equilibria, tonicity, chemical kinetics, rheology, complex formation and interfacial phenomenon are presented. The text also provides an introduction to pharmacokinetics and pharmacodynamics and the principles of absorption, distribution, metabolism and excretion. In addition, some introductory concepts on drug discovery and drug product approval as well as information resources in pharmacy and the pharmaceutical sciences are presented. This book will be useful for anyone interested in pharmaceutics and drug delivery. The focus on the essential concepts of pharmaceutics and drug delivery, however, make this text an exceptionally valuable resource for scientists new to the pharmaceutical industry as well as pharmacy and graduate students.
 

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Contents

Information Resources in Pharmacy and the Pharmaceutical Sciences
1
Analysis of Medicinals
9
Quality Assurance and Control
29
Stability of Pharmaceutical Products
37
Bioavailability and Bioequivalence Testing
51
Dissolution
63
ModernDay Drug Discovery and Development
81
The New Drug Approval Process
93
Rheology
393
Powders
411
Solutions Emulsions Suspensions and Extracts
435
Sterilization Processes and Sterility Assurance
469
Parenteral Preparations
495
Pharmaceutical Compounding USP 797 Sterile Preparations
533
Ophthalmic Preparations
541
Medicated Topicals
565

Metrology and Pharmaceutical Calculations
101
Statistics
133
Molecular Structure Properties and States of Matter
177
Thermodynamics
207
Solutions and Phase Equilibria
219
Separation Methods
241
Ionic Solutions and Electrolytic Equilibria
257
Tonicity Osmoticity Osmolality Osmolarity
277
Chemical Kinetics
301
Complex Formation
317
Interfacial Phenomena
329
Colloidal Dispersions
343
Coarse Dispersions
371
Oral Solid Dosage Forms
581
Coating of Pharmaceutical Dosage Forms
611
Oral ModifiedRelease Drug Delivery Systems
623
Aerosols
633
Biotechnology and Drugs
651
Pharmaceutical Packaging
667
Pharmaceutical Excipients
683
Basic Pharmacokinetics and Pharmacodynamics
705
Drug Action and Effect
727
Drug Absorption Distribution Metabolism and Excretion
739
PharmacokineticsPharmacodynamics in Drug Development
755
Index
763
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